CRISPR is a precise genome editing tool which enables scientists to directly edit DNA within cells.

Targeted Genome Editing - CRISPR

 

CRISPR is a precise genome editing tool which enables scientists to directly edit DNA within cells.

There are two main components of CRISPR: guide RNA and the enzyme Cas9. The guide RNA is specific to the gene to be targeted and directs Cas9 to its complementary DNA sequence. Here, Cas9 creates a break in the DNA which is then fixed by the cell’s natural repair enzymes.

Scientists can use this technology to selectively modify target genes by rewriting their sequence or to switch genes on or off. By modifying the target sequence of the guide RNA one can target different, precise locations in the genome.

CRISPR is a powerful tool that will help us to explore how the genome works and better understand cellular systems and disease. Although still in its infancy, it is hoped that ultimately this technology will be used one day to treat human genetic diseases.

See the BBC News article featuring clips from this animation: http://www.bbc.co.uk/news/health-31010031

More about movie
 
View Next Case Study
CRISPR DNA cutting medical animation
CRISPR DNA Cutting
CRISPR Drug Discovery
CRISPR Genome Editing
CRISPR Histone