Hematologic Malignancies Interactive Challenge
To begin, the user launches a tutorial that takes them on a journey into the bloodstream, learning about the immune response, the CD47-SIRP pathway, and macrophage activity with high-quality 3D graphics. Once the user has studied the signalling processes they move on to the interactive challenge, where they can demonstrate their knowledge by eliminating cancer cells and damaged cells through phagocytosis.
The challenge begins in a blood vessel filled with healthy cells, macrophages, malignant tumor cells, damaged cells, and anti-CD47 antibodies. Using the touchscreen the user can move macrophages through the bloodstream to phagocytose-damaged cells and tumor cells.
The goal is to engulf the damaged cells and complete the challenge.