Immunoproteasome Animation | KZR-616 Selective Inhibitor

SCIENTIFIC ANIMATION | Investor presentations and activities

We created a scientific animation for Kezar Life Sciences focusing on the normal function of the multicatalytic immunoproteasome, emphasizing its importance in the body. The animation then illustrates the disease state, whereby the immunoproteasome becomes highly expressed at the sites of inflammation in patients with autoimmune disorders. The mechanism of action (MoA) of selective inhibitor of the immunoproteasome, KZR-616, is explained and how it induces a potent anti-inflammatory effect, resulting in symptom improvement and disease remission in Rheumatoid Arthritis, lupus, Multiple Sclerosis, and Inflammatory bowel disease.

The purpose of the animation was to provide a visual explanation of the normal function, disease state and MoA of KZR-616 in a comprehensive and engaging manner so that the science and subsequent beneficial outcomes can be clearly understood by the appropriate target audiences.

The animation was created for use at industry trade shows and conferences, for corporate fundraising events and investor relations.

The video can currently be found on the immunoproteasome section of the Kezar Life Sciences website and visual assets utilized throughout their 2019 Investor Presentation.

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cellectar logo

‘‘Extremely happy, everybody was great on the team. They answered all our questions and made it look easy. The end result is perfect.

Executive Coordinator, Cellectar Biosciences


‘‘The presentation was dramatically enhanced by the video, which looked fantastic on the big screen. Thank you and the entire Random42 team for your excellent work and for getting the final edition to me in time for the conference. All very much appreciated!

President and CEO, Vallum Corporation


‘‘The quality of the work produced by Random42 sets them apart and helps us quickly tell our scientific story more clearly. The high-quality production value is bolstered by their depth of knowledge. Together, that helps us tell the story of a complex disease and cell-based treatment and make it understandable to professionals and laypeople alike.’’

CEO, Brainstorm Cell Therapeutics

Phathom logo

‘‘Working with the Random42 team was a seamless collaboration, where they exhibited great project management skills, clear & thoughtful communication, and delivered high-quality work that was visually appealing. Our team was impressed with the final products!’’

Medical Affairs, Phathom Pharmaceuticals